In 2002, Dr. Rui Wang* published research outlining hydrogen sulfide’s crucial role in nerve signaling—a scientific revelation about a substance long-viewed as hostile to life. Since then, hydrogen sulfide has been recognized for its range of key physiological roles, including regulation of energy production and homeostasis in the gastrointestinal, cardiovascular, respiratory, renal, hepatic, and reproductive systems. It also has a central role in managing oxidative stress, acting as a powerful cellular antioxidant in a variety of biological processes. Notably, many diseases feature abnormally increased or decreased hydrogen sulfide production, pointing to potential therapeutic applications.
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* In 2015, Dr. Wang and Dr. John L. Wallace, Antibe’s Chief Scientific Officer, co-authored a paper in Nature Drug Reviews describing therapeutic opportunities for hydrogen sulfide.
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